Kim et al reported the Prognostic Index for Natural Killer cell lymphoma (PINK) for extranodal natural killer T-cell lymphoma (ENKTL). A second score (PINK-E) included information about EBV DNA. The authors are from multiple institutions in Korea.
Patient selection: ENKTL, treated with non-anthracycline-based chemotherapy
Parameters:
(1) age in years
(2) stage
(3) non-nasal disease
(4) distant lymph node involvement
(5) detectable Epstein-Barr virus DNA in blood
Parameter
Finding
Points
age in years
<= 60 years
0
> 60 years
1
stage
I or II
0
III or IV
1
non-nasal disease
no (nasal)
0
yes
1
distant LN involvement
no
0
yes
1
EBV DNA
no
0
yes
1
PINK =
= SUM(points for the first 4 parameters)
PINK-E =
= SUM(points for all 5 parameters)
Interpretation:
• minimum scores: 0
• maximum PINK score: 4
• maximum PINK-E score: 5
PINK
Risk Group
3-Year Overall Survival
0
low
81%
1
intermediate
62%
>=2
high
25%
PINK-E
Risk Group
3-Year Overall Survival
0 or 1
low
81%
2
intermediate
55%
>=3
high
28%
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