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Prognostic Index (PI) of Cahilla et al for Predicting Metastases to Lymph Nodes in Squamous Cell Carcinoma of the Penis

Purpose: To evaluate a man with squamous cell carcinoma of the penis for the probability of lymph node metastases using the prognostic index of Cahilla et al.

Description

Cahilla et al developed a prognostic index (PI) for patients with squamous cell carcinoma of the penis. This can help predict the presence of nodal metastases in inguinal lymph node dissections. The authors are from Instituto de Patologia e Investigacion in Asuncion/Paraguay, and New York University School of Medicine.


Parameters:

(1) histologic grade

(2) anatomic location - glans vs foreskin

 

Parameter

Finding

Points

histologic grade

Grade 1

1

 

Grade 2

2

 

Grade 3

3

anatomic location

glans, in situ

0

 

glans, into lamina propria

1

 

glans, into corpus spongiosum

2

 

glans, into corpus cavernosum

3

 

foreskin, in situ

0

 

foreskin, into lamina propria

1

 

foreskin, into dartos

2

 

foreskin, into adjacent skin

3

 

prognostic index =

= SUM(points for both parameters)

 

Interpretation:

• minimum score: 1

• maximum score: 6

• The higher the score the greater the risk for lymph node metastases.

 

Prognostic Index

Percent of Lymph Nodes Positive for Tumor

1 to 3

0%

4

20%

5

43%

6

71%

 


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Specialty

Objective

ICD-10