Wilbur et al evaluated cancer patients with neutropenic fever. They identified risk factors associated with early death and developed a risk score. The authors are from Loma Linda, California.
Parameters used for risk score:
(1) BUN
(2) maximum pulse
(3) serum LDH
(4) serum glucose
|
Parameter |
Finding |
Points |
|
BUN |
<= 26 mg/dL |
0 |
|
|
> 26 mg/dL |
1 |
|
maximum pulse |
<= 135 beats/minute |
0 |
|
|
> 135 beats/minute |
1 |
|
serum LDH |
<= 550 IU/L |
0 |
|
|
> 550 IU/L |
1 |
|
serum glucose |
<= 170 mg/dL |
0 |
|
|
> 170 mg/dL |
1 |
from Table 3
where:
• The article refers to LDH in units of IU/dL, but the standard is IU/L.
risk score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
• The higher the risk score, the greater the mortality.
|
Risk Score |
% Mortality |
% Survivors |
|
0 |
0% |
100% |
|
1 |
8% |
92% |
|
2 |
41% |
59% |
|
3 |
80% |
20% |
|
4 |
not given |
not given |
from Table 4
Specialty: Infectious Diseases, Hematology Oncology
ICD-10: ,
