Patient selection: ECOG performance status 0 to 2
Outcomes:
(1) progression-free survival (PFS)
(2) overall survival (OS)
Parameters:
(1) epithelial component in histology
(2) stage
(3) ECOG performance stage
|
Parameter
|
Finding
|
Points for PFS
|
Points for OS
|
|
epithelial component
|
yes
|
0
|
0
|
|
|
no
|
42
|
44
|
|
stage
|
Stage 1 to 3
|
0
|
0
|
|
|
Stage 4
|
37
|
38
|
|
ECOG performance
|
0
|
0
|
0
|
|
|
1
|
50
|
50
|
|
|
2
|
100
|
100
|
total score for PFS =
= SUM(points for all 3 parameters)
total score for OS =
= SUM(points for all 3 parameters)
Interpretation:
• minimum scores: 0
• maximum score for PFS: 179
• maximum score for OS: 182
probability of 6 month progression-free survival in percent =
= (0.000583 * ((PFS points)^2)) - (0.3141 * (PFS points)) + 40.3
probability of 6 month overall survival in percent =
= (-0.000662 * ((OS points)^2)) - (0.2001 * (OS points)) + 82.57
