Durot et al reported a prognostic index for predicting survival for a patient with transformed Waldenstrom's macroglobulinemia. The authors are from multiple institutions in Europe, the United States and Israel.
Patient selection: transformed Waldenstrom's macroglobulinemia
Parameters:
(1) platelet count in 10^9/L
(2) previous treatment for Waldenstrom's macroglobulinemia
(3) serum LDH
Parameters
Finding
Points
platelet count
< 100 * 10^9/L
1
>= 100 * 10^9/L
0
previous treatment
no
yes
serum LDH
<= ULN
> ULN
2
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
Total Score
Risk Group
2-Year Survival
0 or 1
low
81%
2 or 3
intermediate
47%
4
high
21%
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Specialty: Hematology Oncology
