Shebani et al evaluated clinical factors associated with survival in patients with carcinoid tumors arising in the gastrointestinal tract. This can help identify patients who may benefit from more aggressive management. The authors are from Massachusetts General Hospital in Boston.
The chief determinant of prognosis is whether it is a malignant carcinoid tumor that metastasizes.
Predictors of metastatic disease:
(1) age
(2) tumor size
(3) depth of invasion (T code from TNM)
(4) location
|
Parameter |
Finding |
Points |
|
age of the patient |
< 50 years of age |
0 |
|
|
>= 50 years of age |
1 |
|
tumor size |
<= 1 cm |
0 |
|
|
> 1 cm |
1 |
|
depth of invasion (T code) |
T1 |
0 |
|
|
T2, T3 or T4 |
1 |
|
location |
appendix |
0 |
|
|
ileojejunum, colon or rectum |
1 |
from Table 3 page 818
Parameters identified in multivariate analysis as predictors of survival:
(1) age of the patient
(2) gender of the patient
(3) metastatic disease to liver and/or lymph nodes
|
Parameter |
Finding |
Points |
|
age of the patient |
< 50 years of age |
0 |
|
|
>= 50 years of age |
1 |
|
gender of the patient |
male |
1 |
|
|
female |
0 |
|
metastatic disease |
absent |
0 |
|
|
present |
1 |
number of poor prognostic factors =
= SUM(points for all 3 parameters)
Specialty: Hematology Oncology, Surgery, general, Endocrinology
ICD-10: ,
