Sevin et al identified prognostic factors for a woman with early cervical carcinoma using a survival tree analysis. This can help identify a woman who may need more aggressive management. The authors are from the University of Miami and Stanford University.
Patient selection: FIGO Stage I and IIA
Parameters:
(1) age of the patient in years
(2) depth of invasion in mm
(3) lymphatic-vascular space involvement (LVSI)
(4) lymph node metastases
|
Age of the Patient |
Depth of Invasion |
LVSI |
Lymph Node Metastasis |
Prognosis |
|
|
<= 6 mm |
|
|
good |
|
< 40 |
> 6 mm |
negative |
|
good |
|
>= 40 |
> 6 mm |
negative |
|
intermediate |
|
|
7 – 20 mm |
positive |
negative |
intermediate |
|
|
> 20 |
positive |
|
poor |
|
|
7 – 20 mm |
positive |
positive |
poor |
where:
• It would seem that not all of the possible combinations are covered.
• The presence of lymph node metastases would seem to increase a good or intermediate risk group to a poor prognosis.
|
Risk Group |
5 Year Disease Free Survival |
|
good |
91% |
|
intermediate |
68% |
|
poor |
43% |
Specialty: Hematology Oncology, Surgery, general, Obstetrics & Gynecology
ICD-10: ,
