Rades et al evaluated women who receive radiotherapy for spinal cord compression caused by metastatic breast cancer. They identified factors which can help to identify outcomes for these patients. The authors are from University Hospital Hamburg-Eppendrof, Dr, Bernard Verbeeten Institute (Tilburg, The Netherlands), Academic Medical Center (Amsterdam), University Hospital Lubeck, Mount Vernon Centre for Cancer Treatment (Northwood, England) and the Mayo Clinic Scottsdale.
Patient selection: metastatic breast cancer causing spinal cord compression
Outcomes measured:
(1) functional outcome
(2) recurrence risk
(3) overall survival
Parameter
Better Functional Outcome`
Worse Functional Outcome
ambulation status prior to radiotherapy
ambulatory
nonambulatory
development of motor deficit
> 14 days
<= 7 days
Parameter
Greater Recurrence Risk
Lower Recurrence Risk
other bone metastases
present
absent
radiotherapy
short course
longer course
Parameter
Better Survival
Worse Survival
visceral metastases
absent
present
ECOG performance scale
0 to 2
3 or 4
development of motor deficit
> 14 days
<= 7 days
motor function after radiotherapy
improved
deteriorated
To read more or access our algorithms and calculators, please log in or register.
