Prognostic Factors of Lerner et al for a Patient with Diffuse Large B-Cell Lymphoma Undergoing Autologous Hematopoietic Stem Cell Transplantation in Second Complete or Partial Remission
Lerner et al reported prognostic factors for a patient with diffuse large B-cell lymphoma (DLBCL) undergoing autologous hematopoietic stem cell transplantation in second complete or partial remission. This can help to identify a patient who may be a candidate for more aggressive or novel therapy. The authors are from the University of Minnesota.
Patient selection: diffuse large B-cell lymphoma in second partial or complete remission, to receive an autologous hematopoietic stem cell transplant
Parameters:
(1) International Prognostic Index determined at the time of relapse (IPI-R)
(2) bone marrow involvement
Parameter
Finding
Relative Risk for Poor Overall Survival
IPI-R
low and low-intermediate risk
1
intermediate-high and high risk
2.4
bone marrow
not involved
1
involved
2.9
Poor overall survival and progression-free survival were associated with these factors.
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