Prognostic factors identified on multivariate analysis:
(1) WHO performance scale
(2) B symptoms (fever, night sweats, weight loss)
|
Parameter
|
Finding
|
Points
|
|
WHO performance scale
|
0 or 1
|
0
|
|
|
2, 3 or 4
|
1
|
|
B symptoms
|
absent
|
0
|
|
|
present
|
1
|
number of poor prognostic factors =
= SUM(points for the 2 parameters)
Interpretation:
• minimum number of poor prognostic factors: 0
• maximum number of poor prognostic factors: 2
Additional factors affecting outcome:
(1) tumor bulk (diameter <= 7 cm better than > 7 cm)
(2) Ann Arbor Stage (I or II better than III or IV)
(3) combination chemotherapy and radiotherapy (optimally >= 45 Gy)
