Prognostic Factors of Kooby et al for a Patient with Gastric Carcinoma and Negative Lymph Nodes

Description

Kooby et al identified a number of prognostic factors for patients with a gastric carcinoma and no evidence of lymph node metastases. These can help to identify patients who may benefit from more aggressive management. The authors are from Memorial Sloan-Kettering Cancer Center in New York City.

Patient selection: gastric carcinoma, adequately staged (with 15 or more lymph nodes, R0 after surgery, T1 to T3 (T4 not included because of limited sample size)

Factors associated with worse disease-specific survival on multivariate analysis:

(1) serosal invasion (T3 stage)

(2) vascular invasion

(3) male gender

(4) resection other than distal subtotal gastrectomy

Additional factors to consider when evaluating prognosis:

(1) nerve invasion (correlates with tumor size and T stage)

(2) T4 (not included in multivariate analysis)

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Description

Specialty

ICD-10