Description

Kahn and Blum identified prognostic factors observed in children with fulminating meningococcemia who did not survive.


 

Patient population: children from 4 months to 12 years of age admitted to a pediatric intensive care unit in Belgium

 

Unfavorable criteria seen in nonsurvivors:

(1) coma stage II or worse (nonrousable child without spontaneous eye movements)

(2) shock (systolic blood pressure < 60 mm Hg)

(3) low or normal initial total blood leukocyte count (<= 10,000 per µL), or low total polymorphonuclear count (<= 2,000 per µL)

(4) thrombocytopenia (platelet count <= 150,000 per µL) and DIC

(5) metabolic acidosis (bicarbonate <= 15 mEq/L and/or pH <= 7.30)

 

Interpretation

Number of Unfavorable Criteria

Percent Survival

0

100%

1

86%

2

66%

3

21%

4

0%

5

0%

(extracted from Figure 1, page 682, and text page 681, Kahn and Blum, 1978)

 


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