Idro et al identified prognostic factors for a child with cerebral malaria admitted to Mulago Hospital in Uganda. These prognostic factors reflect multi-organ failure (MOF). The authors are from Makerere University in Kampala, Uganda.


Patient selection: child with cerebral malaria using the WHO criteria


Mortality rate: 7%


Risk factors for mortality:

(1) respiratory distress

(2) circulatory failure (associated with hypothermia, cold peripheries and dehydration)

(3) generalized hyporeflexia

(4) parasite density in whole blood >= 500,000 per µL


Neurological sequelae were seen in 5% of patients and were associatd with multiple convulsions on admission.


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