Hoogeoud et al reported prognostic factors for a patient presenting with syphilitic uveitis. These factors can help to guide patient management. The authors re from multiple institutions in France.
Patient selection: syphilitic uveitis
Case characteristics:
(1) most often had panuveitis or posterior uveitis
(2) inflammation was greater in HIV positive patients
Criteria for improvement - both of the following:
(1) decrease by 2 or more steps in both anterior chamber and vitreous haze levels (using SUN guidelines)
(2) size reduction of chorioretinal lesions
Criteria for recovery: resolution of inflammation in all anatomic structures at 1 month
65% showed recovery at 1 month and 85% at last follow-up.
Predictors of recovery:
(1) clinical improvement at 1 week (corrected RR 3.5)
The use of periocular dexamethasone injections and methylprednisone pulses had a negative impact on outcomes (cRR for injections was 0.05).
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