Patient selection: nonoliguric acute tubular necrosis
Parameters:
(1) urinary cystatin C in g/L
(2) urinary alpha-1 microglobulin in g/L
(3) urine creatinine in mol/L
ratio of urinary cystatin C to creatinine in g/mol =
= (urine cystatin C in g/L) / (urine creatinine in mol/L)
ratio of urinary alpha-1 microglobulin to creatinine in g/mol =
= (urine alpha-1 microglobulin in g/L) / (urine creatinine in mol/L)
where:
• Dividing the value for mg/dL by 100 gives the value for g/L.
• Dividing the value for mmol/L by 1000 gives the value for mol/L.
• Grams protein per mole creatinine is equivalent to mg protein per mmol creatinine.
The risk of renal replacement therapy is increased if:
(1) cystatin C ratio > 1 g/mol (sensitivity 92%, specificity 83%)
(2) alpha-1 microglobulin ratio > 20 g/mol (sensitivity 88%, specificity 81%)
