Germing et al reported prognostic factors for a patient with chronic myelomonocytic leukemia (CMML). The authors are from Heinrich-Heine University in Dusseldorf.
Parameters:
(1) serum LDH
(2) medullary blast count in percent
(3) sex of the patient
(4) absolute lymphocyte count
(5) hemoglobin in g/dL
Parameter
Finding
Points
serum LDH
low or normal
0
elevated
1
medullary blast count
<= 10%
0
> 10%
1
sex
female
0
male
1
absolute lymphocyte count
<= 2,500 per µL
0
> 2,500 per µL
1
hemoglobin
>= 12 g/dL
0
< 12 g/dL
1
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• The higher the score the worse the prognosis.
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