Description

Fan et al evaluated pediatric patients with Takayasu's arteritis. They identified a number of prognostic factors. The authors are from Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing.


Median age: 14 years

Median BMI: 19.7

 

Sites of major vascular involvement: abdominal aorta; renal, sublcavian, carotid, coronary arteries

 

Outcomes: rehospitalization, vascular complication, flare, death

 

Mortality rate: 3% (mid-aortic syndrome; coronary artery involvement)

 

Poor prognostic factors:

(1) lower BMI at presentation

(2) younger age at presentation

(3) stroke

(4) elevated CRP (above the upper limit of normal)

 

Predictors of events (vascular complications, flares, death):

(1) BMI (HR 0.49)

(2) stroke (HR 7.4)

(3) revascularization (HR 0.51): balloon angioplasty, stenting, bypass graft, valve replacement, pseudoaneurysm repair


To read more or access our algorithms and calculators, please log in or register.