Prognostic Factors of Ewig et al for a Patient with Febrile Neutropenia and Pulmonary Infiltrates During Chemotherapy for Acute Leukemia

 

Parameters:

(1) ratio of heart rate (HR) to systolic blood pressure (SBP)

(2) radiographic score

 

ratio of heart rate to systolic blood pressure =

= (heart rate in beats per minute) / (systolic blood pressure in mm Hg)

 

radiographic score =

= SUM(number of 6 zones showing an infiltrate on the chest X-ray)

Parameters	Findings	Points
HR to SBP ratio	< 1.2	0
	>= 1.2	1
radiographic score	1 or 2	0
	3 to 6	1

 

where:

• The chest X-ray was divided into left and right lung fields, then 2 horizontal lines divided each field into 3 equals regions, for a total of 6 zones.

 

total number of risk factors =

= SUM(points for both parameters)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 2

• The prognosis becomes worse as the number of risk factors increase.