Endorff and Gamelli evaluated patients with inhalation injury associated with thermal burns. The authors are from Loyola University in Maywood, Illinois.
Patient selection: thermal burns
Parameters:
(1) inhalation injury using the grades of Albright et al
(2) PaO2 to FIO2 ratio
The presence of significant inhalation injury (Grades 2 to 4, corresponding to moderate to massive injury) is associated with a worse outcome (with survival of 57% vs 84% for Grades 0 or 1).
A PaO2 to FIO2 ratio < 350 was associated with a higher fluid resuscitation requirement (7.4 mL per kg per percent TBSA; compared to 5.9 if ratio > 350). Survival was worse but did not meet statistical significance.
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