Carter et al evaluated prognostic factors for a patient with an adenocarcinoma at the Ampulla of Vater. These can identify a patient who may benefit from more aggressive management. The authors are from the University of California at San Francisco.
Parameters identified on multivariate analysis:
(1) histologic type
(2) tumor stage
(3) lymphovascular spread
(4) perineural spread
Parameter |
Finding |
Points |
histologic type |
intestinal |
0 |
|
pancreatobiliary |
1 |
stage |
Stage 0 to II |
0 |
|
Stage III or IV |
1 |
lymphovascular spread |
absent |
0 |
|
present |
1 |
perineural spread |
absent |
0 |
|
present |
1 |
total number of adverse prognostic indicators =
= SUM(points for the 4 prognostic factors)
Interpretation:
• minimum number: 0
• maximum number: 4
• The greater the number of adverse prognostic indicators the worse the prognosis.
Specialty: Hematology Oncology, Surgery, general, Gastroenterology