Description

Carter et al evaluated prognostic factors for a patient with an adenocarcinoma at the Ampulla of Vater. These can identify a patient who may benefit from more aggressive management. The authors are from the University of California at San Francisco.


 

Parameters identified on multivariate analysis:

(1) histologic type

(2) tumor stage

(3) lymphovascular spread

(4) perineural spread

Parameter

Finding

Points

histologic type

intestinal

0

 

pancreatobiliary

1

stage

Stage 0 to II

0

 

Stage III or IV

1

lymphovascular spread

absent

0

 

present

1

perineural spread

absent

0

 

present

1

 

total number of adverse prognostic indicators =

= SUM(points for the 4 prognostic factors)

 

Interpretation:

• minimum number: 0

• maximum number: 4

• The greater the number of adverse prognostic indicators the worse the prognosis.

 


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