Parameters associated with reversibility of renal failure:
(1) degree of renal failure
(2) hypercalcemia
(3) level of proteinuria
Factors associated with reversible renal failure:
(1) lower serum creatinine (< 354 µmol/L), indicating mild renal failure
(2) presence of hypercalcemia (>= 2.88 mmol/L)
(3) low urine protein (< 1 gram per 24 hours)
|
Parameter
|
Relative Risk for Reversible Renal Failure
|
95% Confidence Interval
|
p value
|
|
serum creatinine < 354 µmol/L
|
7.5
|
2 to 28
|
0.001
|
|
serum calcium >= 2.88 mmol/L
|
3.27
|
1.1 to 9.3
|
0.02
|
|
urine protein < 1 gram per 24 hours
|
2.78
|
1.09 to 7.08
|
0.02
|
from Table 2, page 1892
Parameters associated with survival after the onset of renal failure:
(1) response to chemotherapy
(2) degree of renal failure
Factors associated with poor survival:
(1) irreversible renal failure (mean survival 28.3 months if reversible; only 3.8 months
(2) treatment failure
|
Renal Failure
|
Mean Survival
|
5 Year Survival Rate
|
|
reversible
|
28.3 months
|
23%
|
|
irreversible
|
3.8 months
|
8%
|
from Figure 2, page 1892
