Prognostic Factors of Behranwala et al for a Soft Tissue Sarcoma of the Buttock

Description

Behranwala et al identified prognostic factors associated with a soft tissue sarcoma involving the buttock. This can help identify a patient who may require more aggressive therapy or who may be a candidate for a novel therapy. The authors are from Royal Marsden Hospital in London.

Histologic types include:

(1) liposarcoma

(2) leiomyosarcoma

(3) synovial sarcoma

(4) malignant fibrous histiocytoma

Features making surgical resection difficult:

(1) proximity to the sciatic nerve

(2) direct extension into the pelvis

(3) adherence to or invasion of the sacrum or pelvic bones

(4) direct extension to the perineum

Parameters affecting prognosis:

(1) diameter of the tumor in cm

(2) differentiation of the tumor

(3) operative margin

(4) presence of distant metastases

(5) location (superficial vs deep)

Parameter	Favorable	Unfavorable
diameter of the tumor	< 5 cm	>= 5 cm
differentiation	Grade I	Grade III
operative margin	wide (completely resected)	positive for tumor (incompletely ressected)
distant metastases	none	present
location	superficial	deep

To read more or access our algorithms and calculators, please log in or register.

Prognostic Factors of Behranwala et al for a Soft Tissue Sarcoma of the Buttock

Description

Specialty