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Prognostic Factors of Bastug et al for a Patient with Crimean-Congo Hemorrhagic Fever (CCHF)

Description

Bastug et al identified prognostic factors for a patient with Crimean Congo Hemorrhagic Fever (CCHF). This can help to identify a patient on hospital admission who may benefit from more aggressive management. The authors are from Ankara Numune Training and Research Hospital in Ankara, Turkey.


Patient selection: Crimean-Congo hemorrhagic fever

 

Outcome: mortality

 

Parameters on hospital admission:

(1) leukocyte count per µL

(2) aPTT in seconds

(3) serum LDH concentration in IU/L

(4) serum ALT concentration in IU/L

 

Parameter

Finding

Points

leukocyte count

<= 2,950 per µL

0

 

> 2,950 per µL

1

aPTT

<= 42.4 seconds

0

 

> 42.4 seconds

1

serum LDH

<= 967.5 IU/L

0

 

> 967.5 IU/L

1

serum ALT

<= 119.5

0

 

> 119.5

1

 

total score =

= SUM(points for the 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 4

• The higher the scores the greater the risk of mortality. The odds ratios ranged from 7.3 to 11.7.

 

Performance:

• The cutoffs may need to be modified for different instruments and methods.


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