Description

Alessandria et al evaluated patients with cirrhosis and the hepatorenal syndrome. They identified prognostic factors associated with 3-month survival. The authors are from multiple institutions in Barcelona, Spain.


Patient selection: hepatorenal syndrome

 

Outcome: 3-month survival

 

Parameters:

(1) MELD score

(2) type of hepatorenal syndrome (Type I or II)

 

Hepatorenal Syndrome

MELD Score

3-Month Survival

absent

< 20

good

absent

>= 20

fair until MELD > 40

Type 1

< 20

guarded

Type 1

>= 20

poor

Type 2

< 20

fair

Type 2

>= 20

guarded until MELD > 30

 

Other factors associated with poor prognosis from the univariate analysis:

(1) serum sodium <= 130 mmol/L

(2) BUN >= 60 mg/dL

(3) CTP score > 10

(4) defects in prothrombin time


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