Alessandria et al evaluated patients with cirrhosis and the hepatorenal syndrome. They identified prognostic factors associated with 3-month survival. The authors are from multiple institutions in Barcelona, Spain.
Patient selection: hepatorenal syndrome
Outcome: 3-month survival
Parameters:
(1) MELD score
(2) type of hepatorenal syndrome (Type I or II)
Hepatorenal Syndrome
MELD Score
3-Month Survival
absent
< 20
good
absent
>= 20
fair until MELD > 40
Type 1
< 20
guarded
Type 1
>= 20
poor
Type 2
< 20
fair
Type 2
>= 20
guarded until MELD > 30
Other factors associated with poor prognosis from the univariate analysis:
(1) serum sodium <= 130 mmol/L
(2) BUN >= 60 mg/dL
(3) CTP score > 10
(4) defects in prothrombin time
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