The prognosis in patients with Ewing Sarcoma of the pelvic bones is affected by the stage of the tumor at presentation, the treatment given and the response to the treatment.
Prognostic Factor
Finding
Effect
extent
localized
good
metastatic
poor (risk ratio 4.1)
therapy
combined modality therapy
good if tumor localized
followed
not as good (risk ratio 1.7)
response to preoperative chemotherapy
good (< 10% tumor viable)
good
poor (>= 10% tumor viable)
poor (risk ratio 3.3)
size
< 100 mL
good
>= 100 mL
poor (risk ratio 4.1); >= 200 worse than 100 - 199
surgical margins
radical or wide
good
marginal or intralesional
not as good (risk ratio 1.3)
Table 5, page 876
where surgical margins are termed:
• intralesional if margins positive;
• marginal if margin is through the reactive tissue about tumor;
• wide if margins negative but within the involved compartment;
• radical if whole tumor-bearing compartment is completely removed
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