Description

The presence of certain risk factors was associated with mortality in patients registered in the International Cooperative Pulmonary Embolism Registry (ICOPER). These can help identify a patient who may require more aggressive management.


 

Risk factors:

(1) age

(2) cancer

(3) congestive heart failure

(4) chronic obstructive lung disease (COPD)

(5) systolic arterial blood pressure

(6) respiratory rate

(7) right ventricular function on echocardiography

Parameter

Finding

Points

age

> 70 years

1

 

<= 70 years

0

cancer

absent

0

 

present

1

congestive heart failure

absent

0

 

present

1

COPD

absent

0

 

present

1

systolic blood pressure

>= 90 mm Hg

0

 

< 90 mm Hg

1

respiratory rate

< 20 breaths per minute

1

 

>= 20 breaths per minute

0

right ventricular function

hypokinesis present

1

 

hypokinesis absent

0

 

 

Risk Factor

Hazard Ratio

95% CI

age > 70 years

1.6

1.1 – 2.3

cancer

2.3

1.5 – 3.5

congestive heart failure

2.4

1.5 – 3.7

COPD

1.8

1.2 – 2.7

systolic BP < 90 mm Hg

2.9

1.7 – 5.0

respiratory rate < 20 breaths/min

2.0

1.2 – 3.2

right ventricular hypokinesis

2.0

1.3 – 2.9

 

total score =

= SUM(points for all 7 risk factors)

 

Interpretation:

• minimum score: 0

• maximum score: 7

• The higher the score the greater the mortality risk.

 


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