A number of factors may indicate a worse prognosis for a patient with a follicular dendritic cell sarcoma/tumor.
Parameters:
(1) intra-abdominal involvement at presentation
(2) cytologic atypia
(3) tumor necrosis
(4) tumor diameter in cm
(5) proliferative index
(6) use of adjuvant therapy
|
Parameter |
Finding |
Points |
|
intra-abdominal involvement |
absent |
0 |
|
|
present |
1 |
|
cytologic atypia |
none or mild |
0 |
|
|
marked |
1 |
|
tumor necrosis |
none or patchy |
0 |
|
|
extensive |
1 |
|
tumor diameter |
<= 6 cm |
0 |
|
|
> 6 cm |
1 |
|
proliferative index |
low |
0 |
|
|
high |
1 |
|
adjuvant therapy |
given |
0 |
|
|
not given |
1 |
total number of poor prognostic factors =
= SUM(points for all 6 parameters)
Interpretation:
• minimum number: 0
• maximum number: 6
• The higher the number of poor prognostic factors the more likely the patient will have a poor prognosis.
Specialty: Hematology Oncology
