Pescarmona et al identified tumor stage and histologic types as prognostic factors for patients with thymoma.
Patients: 83 patients with thymoma seen at the University of Rome between 1965 and 1989.
Parameters found to correlate with prognosis:
(1) histologic type
(2) staging using the method of Masaoka et al.
Major Prognostic Groups
Prognosis
5 Year Survival
10 and 15 Year Survival
medullary type, stages I and II
mixed type, stage I
excellent
100%
90%
cortical type, stages I and II
mixed type, stages II and III
inter-mediate
82%
75%
cortical type, stages III and IV
least favorable
42%
27%
where:
• medullary type stages III and IV not identified
• mixed type stage IV is very rare, with only 1 patient in series
Factors not found to have prognostic significance:
(1) age
(2) gender
(3) presence/absence of myasthenia gravis
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Specialty: Hematology Oncology, Surgery, general
