Guidelines for Using Serum Procalcitonin Concentration to Treat Sepsis

Purpose: To use the serum procalcitonin concentration to guide antibiotic therapy in a patient who is critically ill and septic.

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Evaluation

Are you evaluating a patient who is critically ill and septic?

Yes

Are blood cultures positive?

Yes

Serum procalcitonin concentration at baseline

µg/L

Serum procalcitonin level on day 5

µg/L

Is the patient showing signs of severe infection on day 5?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Ratio of serum procalcitonin at followup to baseline value

Can you discontinue antibiotic therapy?

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Interpretation and Description

References

Next Steps in Evaluation

Monitoring

Response To Therapy

Specialty

Infectious Diseases
Pharmacology, clinical

Objective

options

ICD-10

A40 - Streptococcal sepsis
A41 - Other sepsis
A49.9 - Bacterial infection, unspecified

Info

Purpose: To use the serum procalcitonin concentration to guide antibiotic therapy in a patient who is critically ill and septic.

Specialty: Infectious Diseases, Pharmacology, clinical

Objective: options

ICD-10: A40, A41, A49.9,

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