Malathion is an organophosphate insecticide that can be used to treat lice. It is an effective agent that is ovicidal. However, its use is associated with a number problems.
Mechanism of action: irreversible cholinesterase inhibition
Problems in using malathion:
(1) objectionable odor, which can result in decreased compliance
(2) prolonged application period (up to 12 hours)
(3) flammability
(4) acute toxicity if ingested
(5) possible carcinogenicity with chronic exposure
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