Description

Pediatric risk of mortality (PRISM) score allows for mortality risk assessment in the pediatric ICU. It was developed from the Physiologic Stability Index (PSI), but is intended to be not only simpler but also more objective in its use of physiologic variables. It is institution independent and can be used within limits to compare different intensive care units.


Parameters:

(1) systolic blood pressure and age

(2) diastolic blood pressure

(3) heart rate

(4) respiratory rate

(5) PaO2 to FIO2 ratio

(6) PaCO2

(7) Glasgow coma score

(8) pupillary reactions to light

(9) PT and PTT

(10) total serum bilirubin

(11) serum potassium

(12) serum total calcium

(13) glucose

(14) bicarbonate

 

Parameter

Age Limit

Ranges

Points

systolic blood pressure in mm Hg

infants

130-160

2

 

 

55-65

2

 

 

> 160

6

 

 

40-54

6

 

 

< 40

7

 

children

150-200

2

 

 

65-75

2

 

 

> 200

6

 

 

50-64

6

 

 

< 50

7

diastolic blood pressure in mm Hg

all ages

> 110 mm Hg

6

heart rate in beats per minute

infants

> 160

4

 

 

< 90

4

 

children

> 150

4

 

 

< 80

4

respiratory rate in breaths per minute

infants

61-90

1

 

 

> 90

5

 

 

apnea

5

 

children

51-70

1

 

 

> 70

5

 

 

apnea

5

PaO2/FIO2

all ages

200-300

2

 

 

< 200

3

PaCO2 in torr (mm Hg)

all ages

51-65

1

 

 

> 65

5

Glasgow coma score

all ages

< 8

6

pupillary reactions

all ages

unequal or dilated

4

 

 

fixed and dilated

10

PT/PTT

all ages

1.5 times control

2

total bilirubin in mg/dL

> 1 month

> 3.5

6

potassium in mEq/L

all ages

3.0-3.5

1

 

 

6.5-7.5

1

 

 

< 3.0

5

 

 

> 7.5

5

calcium in mg/dL

all ages

7.0-8.0

2

 

 

12.0-15.0

2

 

 

< 7.0

6

 

 

> 15.0

6

glucose in mg/dL

all ages

40-60

4

 

 

250-400

4

 

 

< 40

8

 

 

> 400

8

bicarbonate in mEq/L

all ages

< 16

3

 

 

> 32

3

 

where:

• infants: 0-1 years of age

• The first implementation of the score had PT and PTT handled as a ratio of PT to PTT. On review it is obvious that the intent is to compare each to the normal control. Unfortunately it is not stated if points are assigned if each is abnormal or if only one.

 

PRISM score =

= (systolic blood pressure points) + (diastolic blood pressure points) + (heart rate points) + (respiratory rate points) + (oxygenation points) + (Glasgow coma score points) + (pupillary reaction points) + (coagulation points) + (bilirubin points) + (potassium points) + (calcium points) + (glucose points) + (bicarbonate points)

 

Interpretation:

• minimum score 0, which has an excellent prognosis

• maximum score 76, which is almost invariably associated with death

 

Prediction of Mortality in ICU

 

R =

= (0.207 * (PRISM score)) - (0.005 * (age in months)) - (0.433 * (operative status)) - 4.782

 

where:

• operative status = 1 if postoperative or = 0 if nonoperative

• upper limit for age used in implementation will be 19th birthday

 

probability of mortality in the ICU =

= EXP(R) / (1 + EXP(R))

 

probability of survival from the ICU =

= 1 - (probability of mortality)

 

Assessment:

• sensitivity: correct prediction of nonsurvival

• specificity: correct prediction of survival

 

Limitations:

• The PRISM score underpredicts deaths after cardiac surgery.


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