Primary Biliary Cirrhosis - AST to Platelet Ratio Index (APRI) & Response to UDCA Therapy for Risk Stratification

Purpose: To evaluate a patient with primary biliary cirrhosis (PBC) based on the study of Trivedi et al.

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Evaluation

Are you evaluating a patient with primary biliary cirrhosis?

Yes

Serum AST as baseline

IU/L

Upper limit of normal for serum AST

IU/L

Platelet count at baseline

Has the patient responded to therapy with UDCA?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

APRI

Is the patient at increased risk for a worse outcome based on the APRI?

The predicted outcome for the patient is

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
- Mayo Risk Score in Primary Biliary Cirrhosis
Clinical Diagnosis, Including Family History For Genetics
- Yale Prognostic Score in Primary Biliary Cirrhosis
Other Testing
Criteria For Diagnosis
- Score for Diagnosis of Primary Biliary Cirrhosis (PBC)
Severity, Prognosis, Stage

Therapy

Selection
- GLOBE Score for Patient with Primary Biliary Cirrhosis (PBC)

Specialty

Gastroenterology
Immunology/Rheumatology

Objective

selection
response to therapy

ICD-10

K74.3 - Primary biliary cirrhosis

Info

Purpose: To evaluate a patient with primary biliary cirrhosis (PBC) based on the study of Trivedi et al.

Specialty: Gastroenterology, Immunology/Rheumatology

Objective: selection, response to therapy

ICD-10: K74.3,

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