Penile lymphoma is a subset of malignant priapism. It may present as a chronic priapism or as a mass lesion.
Involvement of the penis by a malignant lymphoma may be primary or secondary. Primary lymphoma may have a delayed diagnosis because of its rarity.
Most reported cases showed a diffuse large B-cell lymphoma.
It may present as:
(1) chronic priapism, which may be poorly responsive to initial therapy
(2) as one or more nodular lesions, which may also involve the scrotum
It may be accompanied by:
(1) lymphadenopathy
(2) impotence, which may persist after therapy
The diagnosis is typically made by biopsy.
Radiation therapy may be avoided due to concerns about morbidity, relying on chemotherapy for control.
