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Preoperative Risk Score of Sasaki et al for a Patient with Intrahepatic Cholangiocarcinoma

Description

Sasaki et al developed a preoperative score for evaluating a patient undergoing hepatectomy for intrahepatic cholangiocarcinoma. This can help to identify a patient who may or may not benefit from surgery. The authors are from multiple institutions in Japan, Europe, North America, Australia and China,


Patient selection: intrahepatic cholangiocarcinoma

 

Outcome: overall survival after hepatectomy

 

Parameters:

(1) serum albumin in g/dL

(2) neutrophil to lymphocyte ratio (NLR)

(3) CA 19-9 in IU/mL

(4) tumor size in cm

 

preoperative score =

= (0.5 * (NLR)) + (2.81 * (LN(CA19-9))) - (2.79 * (albumin)) + (1.12 * (tumor size)) + 9

 

Inerpretation:

• The higher the score the worse the prognosis.

• A preoperative score >= 30 was associated with a poor prognosis.

 

Score

Category

Median Survival

<= 9

1

> 120 months

10 to 19

2

53 months

20 to 29

3

22 months

30 to 39

4

10.6 months

>= 40

5

5.3 months

from Figure 2

 

Performance:

• The area under the ROC curve was 0.7.


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