The prognosis in patients being evaluated preoperatively for coronary artery bypass surgery can be estimated using a clinical severity score using 13 clinical and laboratory factors.
Preoperative factors evaluated:
(1) age
(2) body weight
(3) emergency need for surgery
(4) history of previous vascular surgery
(5) history of previous heart surgery
(6) history of previous cardiovascular disease
(7) history of chronic obstructive lung disease
(8) history of diabetes mellitus requiring oral drug or insulin therapy
(9) aortic stenosis
(10) mitral insufficiency
(11) severe left ventricular dysfunction
(12) hematocrit
(13) serum creatinine
Preoperative Factor |
Finding |
Points |
---|---|---|
serum creatinine |
< 1.6 |
0 |
|
>= 1.6 to <= 1.8 mg/dL |
1 |
|
>= 1.9 mg/dL |
4 |
emergency case |
yes |
6 |
|
no |
0 |
reoperation |
yes |
3 |
|
no |
0 |
severe left ventricular dysfunction |
present |
3 |
|
absent |
0 |
operative mitral valve insufficiency |
present |
3 |
|
absent |
0 |
age |
< 65 |
0 |
|
>= 65 and <= 74 |
1 |
|
>= 75 |
2 |
prior vascular surgery |
present |
2 |
|
absent |
0 |
chronic obstructive lung disease with use of bronchodilating drugs |
present |
2 |
|
absent |
0 |
anemia (hematocrit <= 34%) |
hematocrit <= 34% |
2 |
|
hematocrit > 34% |
0 |
aortic valve stenosis, operated |
present |
1 |
|
absent |
0 |
body weight <= 65 kilograms |
<= 65 kilograms |
1 |
|
> 65 kilograms |
0 |
diabetes, on oral agent or insulin therapy |
present |
1 |
|
absent |
0 |
cerebrovascular disease |
present |
1 |
|
absent |
0 |
where:
• An emergency case defined as unstable angina, unstable hemodynamics or ischemic valvular dysfunction that could not be controlled medically, complications of percutaneous transluminal angioplasty or complications of cardiac catheterization.
• Reoperation indicates previous surgery on the heart.
• Severe left ventricular dysfunction is associated with an ejection fraction of < 35%.
• Prior vascular surgery includes carotid endarterectomy or heart valve replacement.
• "Aortic valve stenosis, operated" is not described further. I will take it has being a history of surgery for aortic stenosis.
clinical severity score =
= SUM(points for 13 preoperative factors)
Interpretation:
• minimum score: 0
• maximum score: 31
Severity Score |
Morbidity |
Mortality |
---|---|---|
0 |
3% |
< 1% |
1 |
4% |
1% |
2 |
6% |
2% |
3 |
10% |
2% |
4 |
12% |
2% |
5 |
11% |
3% |
6 |
18% |
4% |
7 - 9 |
23% |
7% |
>= 10 |
50% |
27% |
estimated from Figures 1 and 2 pages 2346-2347
Morbidity included one or more of the following:
(1) cardiac complications
(2) need for mechanical ventilation
(3) central nervous system complication
(4) oliguric or anuric renal failure
(5) serious infection
(6) death
Mortality included:
(1) death during hospitalization for surgery, regardless of length of stay
(2) death within 30 days of hospital discharge
Logistic Regression Analysis
The authors developed the clinical severity score from logistic regression analysis for morbidity and mortality associated preoperative factors.
Factor |
Coefficient for Morbidity |
Coefficient for Mortality |
---|---|---|
emergency case |
2.198 |
2.020 |
serum creatinine >= 1.9 mg/dL |
1.043 |
1.306 |
reoperation |
0.894 |
1.066 |
severe left ventricular dysfunction |
0.727 |
1.334 |
mitral valve insufficiency |
0.953 |
0.929 |
age per decade |
0.374 |
0.662 |
diabetes on medication |
0.388 |
|
weight <= 65 kilograms |
0.374 |
|
anemia with hematocrit < 34% |
0.449 |
0.987 |
COPD on medication |
0.387 |
0.872 |
cerebrovascular disease |
0.339 |
|
aortic stenosis, operated |
0.401 |
|
prior vascular surgery |
0.340 |
0.918 |
constant |
-5.073 |
-9.216 |
from Table 2 page 2346
Purpose: To use a clinical severity score based on preoperative factors to evaluate a candidate for coronary artery bypass surgery.
Specialty: Cardiology, Surgery, general
Objective: risk factors, other testing, severity, prognosis, stage, complications, selection
ICD-10: I97.1,