Some women with asthma will regularly have asthmatic symptoms before menstruation.


Synonyms: menstrual-linked asthma (MLA), premenstrual asthma (PMA)


Clinical features:

(1) woman with history of asthma

(2) exacerbation of asthma before the menses


Matsuo et al hypothesized that a drop in serum progresterone during the late luteal phase was the triggering event.


High-dose progresterone therapy can be effective but is associated with troubling side effects.


Long-term use of an oral contraceptive capable of suppressing ovulation may provide effective control of asthma symptoms.


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