Wagner et al reported risk factors for postoperative venous thromboembolism in a woman with endometrial cancer. These can help to identify a patient who may benefit from more aggressive management. The authors are from the Ohio State University.
Patient selection: uterine carcinoma (adenocarcinoma, sarcoma, mixed)
Rate of venous thromboembolism: 1.7%
Predictors of venous thromboembolism risk from multivariate analysis:
(1) advanced tumor stage (FIGO Stage III or IV)
(2) preoperative leukocytosis (> 11 * 10^9/L)
A modified Caprini score was significant for thromboembolism if the score is >= 8.
Additional predictors from univariate analysis:
(1) preoperative hemoglobin < 10 g/dL
(2) adjuvant chemotherapy
(3) high grade histology
(4) open surgery
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Specialty: Hematology Oncology
