Description

Van Herreweghe et al reported predictors for a poor outcome for a patient with acute kidney injury that requires renal replacement therapy. This can help to identify a patient who may benefit from more aggressive management. The authors are from Sunnybrook Health Science Centre and the University of Toronto in Canada.


Patient selection: acute kidney injury (AKI) requiring renal replacement therapy (RRT)

 

Predictors of 2-day mortality after initiation of RRT:

(1) primary diagnosis (see table)

(2) SOFA score (OR 1.29 per point)

 

Primary Diagnosis

Odds Ratio

cardiovascular disease

4.18

GI or liver disease

0.98

neurologic or traumatic

2.59

respiratory

1.55

renal

1

other

3.51

 

Predictors of hospital mortality:

(1) SOFA score (OR 1.29 per point)

(2) Charlson comorbidity index (OR 1.30 per point)

(3) interhospital transfer (OR 0.55)

 


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