Predictors of van Daalen et al for End-Stage Renal Disease (ESRD) in a Patient with Anti-GBM Glomerulonephritis

Description

van Daalen et al evaluated patients with antibodies directed against the glomerular basement membrane (GBM). They identified risk factors for end-stage renal disease during follow-up. The authors are from multiple institutions in Europe, the United States and New Zealand.

Patient selection: anti-GBM glomerulonephritis

Outcome: end-stage renal disease (ESRD) with dialysis dependency

Predictors of ESRD:

(1) dialysis dependency at presentation (odds ratio 3.2)

(2) interstitial infiltrate grades 2 or 3 out of 3 (odds ratio 2.0)

(3) < 50% normal glomeruli

Glomerular Pattern	Outcome
focal (>= 50% normal)	favorable
cellular crescent	guarded
mixed	guarded
sclerotic (>= 50% globally sclerotic)	poor

To read more or access our algorithms and calculators, please log in or register.

Predictors of van Daalen et al for End-Stage Renal Disease (ESRD) in a Patient with Anti-GBM Glomerulonephritis

Description

Specialty