Soares et al identified risk factors associated with hospital mortality for a patient with head and neck cancer admitted to the intensive care unit (ICU). These can help identify a patient who may not benefit from intensive care. The authors are from Instituto Nacional de Cancer (INCA) in Rio de Janeiro, Brazil.
Parameters identified on multivariate analysis:
(1) tumor stage by TNM classification
(2) ECOG performance scale
(3) number of organ failures
(4) type of cancer
Parameter |
Finding |
Odds Ratio |
tumor stage |
Stage I to III |
1 |
|
Stage IV (distant metastases) |
3.8 |
ECOG performance scale |
0 or 1 |
1 |
|
2, 3 or 4 |
5.2 |
number of organ failures |
none |
1 |
|
1 |
2.9 |
|
2 |
(2.9)^2 |
|
3 |
(2.9)^3 |
|
n |
(2.9)^n |
type of cancer |
larynx |
1 |
|
oral cavity |
2.2 |
|
pharynx |
4.4 |
|
other |
3.7 |
cumulative product of odds ratio =
= PRODUCT(odds ratio for all 4 parameters)
Interpretation:
• minimum cumulative odds ratio: 1
• maximum cumulative odds ratio: > 100
• The higher the cumulative odds ratio the greater the chances of in-hospital mortality.
Specialty: Critical Care, Emergency Medicine, Hematology Oncology, Surgery, general
ICD-10: ,