Simsek reported factors predictive of mortality following a non-traumatic splenectomy. These can help to identify a patient who may require more aggressive or alternative management. The author is from Inonu University in Malatya, Turkey.

Patient selection: age >= 18 years, non-traumatic splenectomy


Outcome: death regarded as the direct result of the splenectomy


Predictors of mortality from multivariate analysis:

(1) hematological malignancy (OR 7.2)

(2) emergency surgery (OR 8.3)

(3) leukocytosis (OR 1.1, cutoff unspecified)


An early intervention to avoid emergency surgery is beneficial.


Additional factors from univariate analysis:

(1) older age (>= 60 years)

(2) neutrophil-to-lymphocyte ratio (> 8)

(3) open surgical technique (vs laparoscopic)

(4) transfusion of blood components

(5) anemia

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