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Predictors of Nuzzo et al for Irreversible Transmural Intestinal Necrosis (ITIN) in a Patient with Acute Mesenteric Ischemia (AMI)

Description

Nuzzo et al reported factors predictive of irreversible transmural intestinal necrosis (ITIN) in a patient with acute mesenteric ischemia (AMI). These can help to identify a patient who may benefit from more aggressive management. The authors are from multiple hospitals in France.


Patient selection: acute mesenteric ischemia

 

Predictors:

(1) organ failure (HR 3.1)

(2) serum lactate concentration > 2 mmol/L (HR 4.1)

(3) bowel loop dilation on abdominal CT scan (HR 2.6)

 

Parameters

Findings

Points

organ failure

no

0

 

yes

1

serum lactate concentration

<= 2 mmol/L

0

 

> 2 mmol/L

1

bowel loop dilatation

no

0

 

yes

1

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 3

 

Score

Percent ITIN

0

3%

1

38%

2

89%

3

100%

 

Performance:

• The area under the ROC curve is stated to be 0.936.


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