Lufti et al reported predictors for delayed engraftment following autologous hematopoietic cell transplant. The authors are from the University of Maryland, Moffitt Cancer Center, and University of Florida.
Patient selection: receipt of an autologous hematopoietic cell transplant
Criteria for delayed engraftment - one or more of the following:
(1) platelet count <= 50,000 per microliter
(2) hemoglobin <= 8 g/dL
(3) absolute neutrophil count <= 1,000 per microliter
Non-Hodgkins lymphoma was associated with a high rate of delayed engraftment.
Predictors of delayed engraftment:
(1) transfusion dependence prior to transplant
(2) low-infused CD34+cell dose (< 3 * 10^6 per kg)
(3) low pre-transplant platelet count (< 150,000 per microliter)
(4) maintenance therapy
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