Lee et al reported risk factors for low adherence for oral 5-aminosalicylic acid (5-ASA) in a patient with ulcerative colitis. This can help to identify a patient who may benefit from interventions to improve compliance. The authors are from multiple institutions in South Korea.
Patient selection: ulcerative colitis with prescription for oral 5-aminosalicylic acid
Frequency of low adherence: 50%
Predictors of low adherence in women:
(1) age less than 40 years of age (OR 3.7)
Predictors of low adherence in men:
(1) excessive alcohol use (OR 2.1)
(2) current smoking (OR 5.1)
A patient with ulcerative colitis should avoid smoking and drinking.
The prescribing physician should periodically review adherence and try to remove barriers to adherence.
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