Hasper et al identified prognostic factors associated with neurologic outcome following cardiac arrest. These can help to identify patients with better or worse prognosis. The authors are from Charite-Universitatsmedizin Berlin.
Outcome: neurological outcome good (Cerebral Performance Category 1 or 2) vs poor (CPC 3 to 5)
Prognostic factors:
(1) difference in serum creatinine on admission and at 24 hours after admission
(2) serum NSE (neuron specific enolase) at 72 hours
change in serum creatinine =
= (serum creatinine in mg/dL at 24 hours) - (serum creatinine in mg/dL on admission)
Prognostic Factors
Favorable
Unfavorable
change in serum creatinine at 24 hours
< - 0.19 mg/dL
>= 0 mg/dL
serum NSE at 72 hours after admission
<= 24 µg/L
>= 29 µg/L
where:
• A drop in creatinine after admission is associated with a good prognosis.
Other factors associated with a better prognosis:
(1) use of therapeutic hypothermia
(2) ventricular fibrillation as initial rhythm
(3) bystander CPR
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