Guzman et al reported risk factors for 30-day readmission for a patient with Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN). This can help to identify a patient who may benefit from more aggressive management. The authors are from Albert Einstein College of Medicine, Johns Hopkins Univresity and Ohio State University.

Patient selection: Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis


Rate of readmission: 10%


Reasons for readmission include:

(1) systemic infection

(2) cutaneous infection

(3) relapse of SJS or TEN

(4) other dermatologic condition

(5) organ dysfunction (GI, cardiac, pulmonary, renal, endocrine, neurologic, other)


Risk factors for readmission:

(1) age from 45 to 64 years (OR 1.9)

(2) Medicaid insurance (OR 1.8)

(3) non-Metropolitanhospital admission (OR 1.7)

(4) comorbid conditions


Comorbid conditions include:

(1) HIV/AIDS (OR 2.5)

(2) collagen vascular disease (OR 2.4)

(3) metastatic cancer (OR 2.2)


The risk of readmission increases with the number of risk factors and comorbid conditions

To read more or access our algorithms and calculators, please log in or register.