Subacute stent thrombosis is recurrent ischemia with documented vessel occlusion within 7 days after a successful percutaneous intervention at the site of a stent placement.
A successful percutaneous intervention (PCI):
(1) post-treatment with antegrade TIMI-3 flow
(2) angiographic residual stenosis < 50%.
The mean reference diameter is the mean of arterial diameters for several segments before and after the lesion.
percent diameter stenosis =
= 100% * (1 - ((minimal lumen diameter in mm)/ (mean reference diameter in mm)))
Risk factors for subacute stent thrombosis:
(1) noncalcified lesion
(2) inadequate luminal expansion after the PCI (minimal luminal area)
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Reference Area (Diameter)
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Minimal Luminal Area as Percent of Reference Area (MUSIC criteria)
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<= 9.0 square mm (<= 3.38 mm)
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< 90%
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> 9.0 square mm (> 3.38 mm)
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< 80%
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Causes for stent thrombosis - one or more of the following:
(1) dissection
(2) thrombus
(3) tissue protrusion within the stent struts
