Agrawal et al reported predictors of 30-day readmission for a patient with infective endocarditis (IE). These can help to identify a patient who may benefit from more aggressive management. The authors are from multiple institutions in the Untied States.

Patient selection: hospitalized patient with infective endocarditis


Rate of readmission: 24%

In-hospital mortality after readmission: 13%


Predictors of readmission from multivariate analysis:

(1) female sex (OR 1.1)

(2) Staphylococcus aureus as cause of the endocarditis (OR 1.1)

(3) diabetes (OR 1.1)

(4) chronic lung disease (OR 1.2)

(5) chronic liver disease (OR 1.2)

(6) renal failure (OR 1.3)

(7) acute heart failure (OR 1.2)

(8) anemia (OR 1.1)

(9) Gram-negative endocarditis (OR 1.1)

(10) rheumatological disorder (OR 1.1)

(11) disposition to facility (OR 1.1)


Multiple risk factors are necessary to significantly impact risk.


Most common reasons for readmission:

(1) sepsis

(2) acute heart failure

(3) acute kidney injury

(4) infection of an intracardiac device

(5) recurrent endocarditis

(6) neurological complications

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