Predictive Model of Ohn et al for the Diagnosis of Subungual Melanoma in Situ

Description

Ohn et al reported a model predictive of subungual melanoma in situ. This can help to identify a patient who should undergo a more complete evaluation. The authors are from Seoul National University, University of Wisconsin-Milwaukee, and Stanford University.

Patient selection: subungual pigmentation

Outcome: longitudinal melanonychia vs subungual melanoma in situ

Method of analysis: dermoscopy

Parameters:

(1) width of the pigmentation in mm

(2) multicolor pigmentation

(3) asymmetry

(4) border fading

(5) Hutchinson's sign (periungual pigmentation of the nail fold or hyponychium)

Parameter	Finding	Points
width of pigmentation	< 3 mm	0
	>= 3 to 5.9 mm	1
	>= 6 mm	2
multicolor pigmentation	absent	0
	present	1
asymmetry	absent	0
	present	2
border fading	absent	0
	present	1
Hutchinson's sign	negative	0
	positive	2

total score =

= SUM(points for all 5 parameters)

Interpretation:

• minimum score: 0

• maximum score: 8

• The higher the score the greater the risk of subungual melanoma.

Score	Sensitivity	Specificity
>= 0	1.00	0
>= 1	1.00	0.23
>= 2	1.00	0.50
>= 3	0.89	0.62
>= 4	0.84	0.73
>= 5	0.84	0.82
>= 6	0.79	0.92
>= 7	0.42	1.00
8	0.32	1.00

Performance:

• The reported area under the ROC curve is 0.91.

To read more or access our algorithms and calculators, please log in or register.

Predictive Model of Ohn et al for the Diagnosis of Subungual Melanoma in Situ

Description

Specialty