Description

Gupta et al reported a predictive model for extubation readiness of an extremely preterm infant. The authors are from Wayne State University.


Patient selection: extremely premature infant from 23 to 33 weeks of gestation

 

Parameters:

(1) gestational age in weeks from 23 to 33 (completed week, as integer)

(2) pre-extubation FIO2 as a percent (from 21 to 100)

(3) highest respiratory severity score (RSS) in first 6 hours of life (mean airway pressure in cm water times FIO2 as decimal fraction, from 1 to 21)

(4) extubation day of life

(5) pre-extubation arterial blood gas pH (odds ratio 1.68 per increase in pH of 0.1)

(6) weight at extubation in grams

 

Parameter

Points

gestational age in weeks

0.40635 * (gestational age)

percent oxygen

-0.0701 * (percent oxygen)

respiratory severity score

-0.1273 * (respiratory severity score)

extubation day of life

0.04202 * (day of life)

arterial blood gas pH

0.52154 * 10 * (pH)

weight at extrubation in grams

0.0016 * (weight)

 

X =

= SUM(points for all 6 parameters) - 47.379

 

probability of successful extubation =

= 1 / (1 + EXP((-1) * X))


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